Dr. Edimara S. Reis
E: edireis@upenn.edu
T: (215)-746-5767
F: (215)-573-8738

Edimara S. Reis, Ph.D.



Current Position

Postdoctoral Researcher

Education

Postdoctoral Fellow, Institute for Systemic Inflammation Research, University of Lubeck, Germany (2010)

PhD, Institute of Biomedical Sciences, University of Sao Paulo, Brazil, Immunology (2008)


Research




Publications

Qu H, Ricklin D, Bai H, Chen H, Reis ES, Maciejewski M, Tzekou A, Deangelis RA, Resuello RR, Lupu F, Barlow PN, Lambris JD. (2013). New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. Immunobiology 218: 496-505. Additional Links: Supplement.
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Abe T, Hosur KB, Hajishengallis E, Reis ES, Ricklin D, Lambris JD, Hajishengallis G. (2012). Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist. Journal of immunology 189: 5442-8.
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Reis ES, Chen H, Sfyroera G, Monk PN, Khl J, Ricklin D, Lambris JD. (2012). C5a receptor-dependent cell activation by physiological concentrations of desarginated c5a: insights from a novel label-free cellular assay. Journal of Immunology 189: 4797-805. Additional Links: In this Issue.
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Reis ES, Lange T, Kohl G, Herrmann A, Tschulakow AV, Naujoks J, Born J, Kohl J. (2011). Sleep and circadian rhythm regulate circulating complement factors and immunoregulatory properties of C5a. Brain, behavior, and immunity 25: 1416-26.
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Weaver DJ, Reis ES, Pandey MK, Kohl G, Harris N, Gerard C, Kohl J. (2010). C5a receptor-deficient dendritic cells promote induction of Treg and Th17 cells. European journal of immunology 40: 710-21.
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Aguilar-Ramirez P, Reis ES, Florido MP, Barbosa AS, Farah CS, Costa-Carvalho BT, Isaac L. (2009). Skipping of exon 30 in C5 gene results in complete human C5 deficiency and demonstrates the importance of C5d and CUB domains for stability. Molecular immunology 46: 2116-23.
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Klos A, Tenner AJ, Johswich KO, Ager RR, Reis ES, Kohl J. (2009). The role of the anaphylatoxins in health and disease. Molecular immunology 46: 2753-66.
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Amano MT, Ferriani VP, Florido MP, Reis ES, Delcolli MI, Azzolini AE, Assis-Pandochi AI, Sjoholm AG, Farah CS, Jensenius JC, Isaac L. (2008). Genetic analysis of complement C1s deficiency associated with systemic lupus erythematosus highlights alternative splicing of normal C1s gene. Molecular immunology 45: 1693-702.
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Falcao DA, Reis ES, Paixao-Cavalcante D, Amano MT, Delcolli MI, Florido MP, Albuquerque JA, Moraes-Vasconcelos D, Duarte AJ, Grumach AS, Isaac L. (2008). Deficiency of the human complement regulatory protein factor h associated with low levels of component C9. Scandinavian journal of immunology 68: 445-55.
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Reis ES, Barbuto JA, Kohl J, Isaac L. (2008). Impaired dendritic cell differentiation and maturation in the absence of C3. Molecular immunology 45: 1952-62.
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Reis ES, Barbuto JA, Isaac L. (2007). Complement components, regulators and receptors are produced by human monocyte-derived dendritic cells. Immunobiology 212: 151-7.
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Reis ES, Barbuto JA, Isaac L. (2006). Human monocyte-derived dendritic cells are a source of several complement proteins. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 55: 179-84.
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S Reis E, Falcao DA, Isaac L. (2006). Clinical aspects and molecular basis of primary deficiencies of complement component C3 and its regulatory proteins factor I and factor H. Scandinavian journal of immunology 63: 155-68.
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Reis ES, Nudelman V, Isaac L. (2004). Nonsense-codon-mediated decay in human hereditary complement C3 deficiency. Immunogenetics 55: 667-73.
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Da Silva Reis E, Baracho GV, Sousa Lima A, Farah CS, Isaac L. (2002). Homozygous hereditary C3 deficiency due to a premature stop codon. Journal of clinical immunology 22: 321-30.
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Ulbrich AG, Florido MP, Nudelman V, Reis ES, Baracho GV, Isaac L. (2001). Hereditary human complement C3 deficiency owing to reduced levels of C3 mRNA. Scandinavian journal of immunology 53: 622-6.
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